CR, June 1, 2001

Combinatorial Chemistry

Outline for today's lecture


 




Reactions on solid supports
 

1. Overview over types of solid supports

2. Polystyrene-based resins, polyacrylamide-based resins, and controlled pore glass

3. Supports with traceless linkers

4. Safety catch linkers
 
 

key references

1. Hudson, D. J. Combin. Chem. 1999, 1, 333-360.

2. Hudson, D. J. Combin. Chem. 1999, 1, 404-457.

3. Czarnik, A.W. Biotechnol. Bioeng. (Comb. Chem.) 1998, 61, 77-79.

4. Woolard, Paetsch & Ellman, J. Org. Chem. 1997, 62, 6102-6103.