CR, January 24, 2001

Nucleic Acids Chemistry

Outline of Today's Lecture
 

Antisense Inhibition of Gene Expression

1.  Gene Expression and Central Dogma of Molecular Biology
2.  Discovery of Antisense Inhibition in the 1970s
3.  First Generation Antisense Agents
4.  Second Generation Antisense Agents
5.  Antigene-Oligonucleotide Inhibitors