CR, November 8, 2000

Nucleic Acids Chemistry

Outline of Today's Lecture
 

Chemical Synthesis of Nucleotides
 

1.  Retrosynthetic Considerations

2.  Glycosylation Methods

 -  Classical methods
 -  Vorbrüggen glycosylation
 -  Anchimeric effect and stereoselectivity
 -  Phosphorylation

3.  Synthesis of C-Nucleosides