CR, 7. November 2002


Nucleic Acids Chemistry


Outline of Today's Lecture
 

Chemical Synthesis of DNA and RNA
 

1.  Retrosynthetic Considerations

2.  Coupling Methods

     -  Phosphotriester method

     -  H-Phosphonate method

     -  Phosphoramidite method
 

3.  Solid-Phase Synthesis of DNA
 

( 4.  Solid-Phase Synthesis of RNA )