CR, 13. April 2005

Nucleic Acids Chemistry

Outline of Today's Lecture

Introduction to Nucleic Acid Structure

1.  The Structure of DNA

 -  2-Deoxyribose, nucleobases, phosphate

 -  2'-Deoxynucleosides and -nucleotides

 -  Numbering scheme, trivial names

  -  Nucleosidetriphosphates

2.  The Structure of RNA

 -  Ribose, phosphate, nucleobases

 -  Nucleosides and nucleotides

 -  Rare nucleobases

3. The Basicity and Acidity of Nuclebases and  Nucleotides

Reference: chapter 2 of Saenger