CR, February 8, 2007


Nucleic Acids Chemistry

Outline of Today's Lecture
 

12. DNA and Nanotechnology
 

12.1  DNA duplexes as nanostructures

     -  Size and shape of DNA

     -  Assembly of unmodified DNA into topological
        objects and two-dimensional arrays
 

12.2  Two-dimensional structures of DNA hybrids

     -  Synthesis of DNA-core hybrids

     -  Nanostructures formed with organic cores
 

12.3  Gold nanoparticles with DNA ligands

     -  Detection of sequences through aggregation

     -  Sorting of nanoparticles onto surfaces
 

12.4  Solubilizing Carbon Nanotubes with DNA

     -  Sequence dependence
 

Selected references: Feldkamp, Niemeyer, Angew. Chem. 2006, 118, 2.
                                Rosi, Mirkin Chem. Rev. 2005, 105, 1547.
                                Seeman, Nature 2003, 421, 427.