CR, 26. Oktober 2006

Nucleic Acids Chemistry

Outline of Today's Lecture
 

Introduction to Nucleic Acid Structure

1.  The Structure of DNA

     -  2-Deoxyribose, nucleobases, phosphate

     -  2'-Deoxynucleosides and -nucleotides

     -  Numbering scheme, trivial names

      -  Nucleosidetriphosphates
 

2.  The Structure of RNA

     -  Ribose, nucleobases, nucleotides

     -  Rare, modified nucleobases
 

3.  Secondary Structure of DNA and RNA

     -  Duplexes: A- and B-form
 

References:  chapters 1 and 9 in Saenger
                    chapter 2 in Blackburn & Gait
                    chapter 29 in Voet & Voet