ChipCheck calculates the expected hybridization
results for small DNA microarrays.
This is version 2.0 of the program, capable of
automatically generating thermodynamic data from
sequence-information and experimental conditions.
The motivation for writing ChipCheck is explained in a brief
introduction to the earlier
For a detailed description of the earlier version, please see the
publication on ChipCheck
ChipCheck can be used on two different levels:
- calculating the extent of binding of target
strands to spots at one, fixed temperature,
- calculating binding (=melting) curves
over an entire temperature range.
Choose from the following list how to invoke ChipCheck (according to the data you provide).
Sequence Entry Page
(if unsure, try this first)
Only sequence information needed. Will produce data file for ChipCheck and assign it an unique ID.
Thermodynamic Data Entry Page
You must supply a data file containing thermodynamic data
for every possible duplex.
Will show the result of a single experiment.
View the results of a single experiment using the experiment-ID
Enter the ID assigned to a previously generated data-file:
View full binding profiles (enter previously assigned ID)
- Edit your datafile:
Last modified: Fri Jan 12 21:54:56 CST 2007