News


In November 2022 Kim Stryk and Jan Hartenfels join the RRG as graduate students.


Vasiliki Krupp successfully defends his Ph.D. thesis (October 2022).


In May 2022 Humayra Bushra joins the RRG as graduate student and Arnab Battachyya as postdoctoral researcher


The Richert Group's crystallization chaperones TEO, TDA and TBro are becoming available commercially.

Crystal lattice of co-crystal of farnesol and TBro, with details of the high resolution structure on the right-hand side. The co-crystal was readily obtained by brief heating and cooling


In February 2022 Adrian Humboldt joins the RRG as graduate student.


In November 2021 Franziska Welsch joins the RRG as graduate student.


Daniel Pfeffer successfully defends his Ph.D. thesis (September 2021).


RRG publishes paper in Nature Chemistry.

A commentary highlighting this work can be found in the same issue of the journal.

Please see our blog entry for background information and explanations.


Maximilian Räuchle and Felix Krupp successfully defend their Ph.D. theses (July 2021)


The Richert Research Group and the Institute mourn the loss of Prof. Dr. Volker Jäger (22.09.1942 - 19.03.2021). Professor Jäger was Clemens' predecessor and chair of Organic Chemistry from 1992-2007. His sudden death is a blow to our community, of whom he continued to be a visible member. The University of Stuttgart and Organic Chemistry as a whole lost an eminent scientist and a person who will remain dear to our hearts.

Prof. Dr. Volker Jäger


Sebastian Motsch successfully defends his Ph.D. thesis (March 2021)


In February 2021 Tim Berking joins the RRG as graduate student.


In November 2020 Dustin Dittrich joins the RRG as graduate student.


The Richert Group, in collaboration with the Bailer Group, publishes new C-nucleoside with antiviral activity.


In October 2020 Tim Gniech joins the RRG as a graduate student.


Paper on key phosphoramidate metabolites, relevant for new ProTide antivirals.


In August 2020 Sabrina Lorenz joins the RRG as a graduate student.


Manpreet Wolfrum successfully defends his Ph.D. thesis (July 2020)


Group picture of members of the RRG in July 2020.


RRG surprises Clemens with 25Y celebration cake on July 17.


Tobias Feldner successfully defends his Ph.D. thesis (July 2020)


May 2020: RRG achieves breakthrough in determining the absolute configuration of small molecules.

Co-crystallization procedure using farnesol as analyte and TBro as crystallization chaperone.


Spring 2020: Institute of Organic Chemistry produces disinfectants for physicians in the State of Baden-Württemberg.

For additional informations see: ViewPoint Paper.

Image from our chemistry stockroom in early April.


Maren Bechthold successfully defends her Ph.D. thesis (March 2020)


February 10th 2020: relaunch of RRG homepage with new design (Daniel)


C-Nucleoside with high affinity for adenine commercialized by Glen Research.


The Richert Research group hosts the TOCUS 2019.

Impression from TOCUS 2019, Oktober 11th, at the University of Stuttgart.
Picture taken by Jennifer.


Cover story in Chemistry European Journal on turning DNA binding motifs into a material for flow cells
Link to the paper


In August 2019 Jianyang Han started his PhD.


Summer 2019: The RRG welcomes Dr. Carolina Sánchez Rico as postdoctoral researcher in our labs at the University of Stuttgart.


Rainer Joachim Schwarz successfully defends his Ph.D. thesis (February 2019)


Recent Additions to the Richert Research Group

  • Juri Eyberg (Spring 2019)
  • Gabrielle Leveau (Winter 2018)
  • Olivia Doppleb (Winter 2018)

  • Summer 2018: The RRG welcomes Dr. Biswarup Jash as postdoctoral researcher in our labs at the University of Stuttgart.


    RRG members rock the graduation party on July 13th 2018.
    Pictures taken by Jennifer.


    Marilyne Sosson successfully defends her Ph.D. thesis (June 2018)


    RRG publishes the first enzyme-free replication of genetic sequence based on nucleotides.
    See link to our paper.


    Spring 2018: The RRG welcomes Jacqueline Ruppert, Franka Topp, Esin Celebi and Madeleine Schwarz to perform their experimental bachelor theses in our labs as part of the Bachelor in Chemistry at the University of Stuttgart.


    Recent Additions to the Richert Research Group

  • Jennifer Bremer (Spring 2018)
  • Felix Krupp (Winter 2017)
  • Daniel Pfeffer (Winter 2017)
  • Maximilian Räuchle (Winter 2017)
  • Dejana Jovanovic (Winter 2017)

  • Shilliang He successfully defends his Ph.D. thesis (March 2018)


    Markus Kramer successfully defends his Ph.D. thesis (December 2017)


    Paper on chemical ligation in nanostructure is "Most Accessed" paper in Chemistry & Biodiversity in October 2017
    Link to the paper


    Mario Jauker successfully defends his Ph.D. thesis (November 2017)


    Clemens talks with Nobel laureate Jean-Pierre Sauvage during the TOCUS at U. Stuttgart in October 2017


    Cover story in Chemistry & Biodiversity on enzyme-free ligation of 5'-phosphorylated oligodeoxynucleotides in a DNA nanostructure
    Link to the paper


    Cover story in European Journal of Organic Chemistry on the solution-phase synthesis of branched oligonucleotides with up to 32 nucleotides and the reversible formation of materials
    Link to the paper


    Alexander Schwenger defends his Ph.D. thesis successfully (May 2017)


    Two papers on RNA-induced peptide formation in the absence of enzymes appear back-to-back in Angewandte Chemie (published online, December 2016)
    Link to first paper
    Link to second paper


    Richert Research Group is awarded major grant from Volkswagenstiftung for research on 'Molecular Life' (December 2016)


    Cover story in Angewandte Chemie on reagents with a crystalline coat.
    Link to the paper


    Anja Göckel defends her Ph.D. thesis successfully (July 2016)


    Rüdiger Haug defends his Ph.D. thesis successfully (April 2016)


    Claudia Gerlach defends her Ph.D. thesis successfully (February 2016)


    Two papers on the spontaneous formation of biomolecules in aqueous buffer appear back-to-back in Angewandte Chemie (November 2015)
    Link to first paper
    Link to second paper
    Link to press release.


    New 700 MHz NMR spectrometer installed (Spring 2015).
    Link to press release of the University of Stuttgart.

    The instrument includes a cryogenic probe and was purchased with funding from DFG. Clemens was the coordinator of the multi-PI proposal with help from Dr. Birgit Claasen.
    The instrument is in newly renovated and air-conditioned space in our building.


    Sebastian Spies and Christoph Kröner both defend their Ph.D. theses successfully (December 2014)


    Andreas Kaiser defends his Ph.D. thesis successfully (November 2014)



    Pictures from the retirement farewell celebration for Mrs. Kraschewski-Fien March 2014.


    Clemens talks shop with Nobel laureate Jean-Marie Lehn during the TOCUS meeting at U. Stuttgart in October 2013.


    Simone Egentenmeyer defends her Ph.D thesis successfully (Oktober 2013)


    Mrs. Kraschewski-Fien celebrates 40 years of service at the University of Stuttgart. Congratulations from the RRG! (Oktober 2013)


    Cora Prestinari defends her Ph.D. thesis successfully. (July 2013)


    Andreas has been selected as one of the finalists for the 2013 Reaxys PhD Prize. (July 2013)


    Heike Vogel defends her Ph.D. thesis successfully. (February 2013)


    Clemens heads organizing committe for DNG symposium at Bad Herrenalb on October 01/02 2012.


    Maryan defends his Ph.D. thesis successfully (July 2012)


    Paper on primer extension with reversible termination highlighted in press release and as back cover of Angewandte Chemie.


    Katja defends her Ph.D. thesis successfully (April 2012)


    Richert Group receives ion trap LC-MS instrument (March 2012).


    Richert Group receives second MALDI-TOF mass spectrometer (December 2011).


    Arunoday Singh defends his Ph.D. thesis successfully (November 2011).


    Richert Group hosts the 15th TOCUS Symposium.


    Deutsche Nucleinsäurechemiegemeinschaft e.v. (DNG) now has its own domain. See dnarna.de or www.nucleinsaeurechemie.de.



    Paper on RNA copying published in Nature Chemistry. See link to our paper. The report is the culimination of five years of research, largely performed by Christopher, who never gave up when it came to demonstrating that RNA can do it all by itself.




    Spring/summer 2011: The RRG welcomes the first four students to perform their experimental bachelor theses in our labs as part of the new Bachelor in Chemistry at the University of Stuttgart.


    Recent Additions to the Richert Research Group

  • Sven Vollmer (Spring 2011)
  • Anja Göckel (Spring 2011)

  • The University of Stuttgart highlights recent advances on the branched DNA hybrids project. See link .


    Clemens mourns the loss of his mentor Prof. Dr. Dr. h.c.mult. Emanuel Vogel (02.12.1927 - 31.03.2011).
    - We will keep the memory of one of the great organic chemists of the 20th century -

    Prof. E. Vogel in 2006


    The Centre for Higher Education Development (CHE) ranked departments and universities in Europe. Chemistry at the University of Stuttgart was ranked in the top group. See

    link .


    Recent Additions to the Richert Research Group

  • Claudia Gerlach (Fall 2010)
  • Hassan Said (Fall 2010)

  • Welcome to our renovated labs

    The first renovated labs at U. Stuttgart were opened for research on September 28, 2010. The picture shows Cora and Heike at work.


    Farewell to Karlsruhe

    Clemens hands over the keys to the Karlsruhe labs to his successor Achim Wagenknecht on September 24, 2010.


    July, 2010 Christopher Deck wins honors degree for Ph.D. thesis.
    At his defense, Christopher got a "summa cum laude" as doctoral degree.



    Paper on templating efficiency of DNA published in PNAS


    Our paper entitled "Templating efficiency of naked DNA" appeared in the Proceeding of the National Academy of Sciences USA;

    Link to Paper and press release.


    Paper on chemical primer extension selected for cover of J. Org. Chem.


    Our paper entitled "Chemical primer extension at submillimolar concentration of deoxynucleotides" by Manuel and Clemens was selected as Featured Article and cover (issue 12, 2010) of JOC (DOI: 10.1021/jo1002467).



    Richert Group Hosting Symposium in May 2010

    We are proud to announce that we will be hosting a one day Symposium on Functional Nucleic Acids on

    May 25, 2010

    at the IBZ Center in Stuttgart, Germany.

    Please contact Gisela Kraschewski-Fien at lehrstuhl-2oc.uni-stuttgart.de for reservations and details.


    Recent Additions to the Richert Research Group

  • Marco Minuth (Spring 2010)

  • Recent Additions to the Richert Research Group

  • Christoph Kröner (Winter 2010)

  • Nachruf

    Ich habe die traurige Pflicht mitzuteilen,
    dass unser liebes langjähriges Gruppenmitglied
    Siegfried Herzberger, geboren 25.01.1942,
    am 22.07.2009 in Konstanz verstorben ist.
    Siegfried wurde Ende 2007 pensioniert und lebte
    zuletzt wieder an dem von ihm geliebten Bodensee.

    - Siegfried Du fehlst uns. Wir werden Dein Andenken bewahren. -

    C.R.


    Best molecular cap to date

    Click here to view the article by Amritraj Patra and Clemens Richert in J. Am. Chem. Soc. 2009.


    Richert Research Group is attending the IV. Nucleic acid meeting in Regensburg 2009.

    Click here for further information.


    Recent Additions to the Richert Research Group

  • Cora Prestinari (Spring 2009)
  • Sebastian Spies (Spring 2009)

  • III. Nucleinsäurechemie-Treffen

    Richert Research Group hosts the 2008 national nucleic acid chemistry meeting

    Click here for further details.


    Recent Additions to the Richert Research Group

  • Heike Vogel (Summer 2008)
  • Simone Egetenmeyer (Summer 2008)
  • Rüdiger Haug (Summer 2008)

  • The Richert Research Group is moving!

    The Richert Research Group proudly announces its move to the University of Stuttgart.


    Recent Additions to the Richert Research Group

  • Mariyan Tolev (Summer 2007)
  • Arunoday Singh (Spring 2008)
  • Andreas Kaiser (Spring 2008)

  • Ulrich selected as award finalist

    Ulrich Plutowski was selected as finalist for the DSM Science and Technology Award 2007.


    Pictures from our April 2007 retreat online

    Pictures taken at our recent retreat and during the 2006 holiday party are now online.


    Publication on spontaneous replication steps selected as "hot paper"

    A recent publication in Chemical communications on spontaneous replication steps of RNA has been selected for presentation as "hot paper":
    M. Spencelayh, RNA on ice. RSC Chemical Biolology, 2007, 2, B41 (cover story).


    Recent Additions to the Richert Research Group

  • Matthias Bauer (Winter 2006)
  • Katja Imhof (Spring 2007)


    University of Karlsruhe secures grant as "Eliteuniversität"

    The University of Karlsruhe (TH) was chosen as one of three institutions in Germany to receive funding in all three lines of excellence funding, including the most prestigous category of "Eliteuniversität", as announced by DFG on October 10, 2006. Funding totals > 20 million € per year. The Richert Research Group was involved on the level of proposal writing and defending the proposal at a hearing in Bonn.


    Recent Additions to the Richert Research Group

  • Martin Meng (Summer 2006)
  • Katharina Müller (Summer 2006)
  • Andreas Schuler (Fall 2006)
  • Pierre Keller (Fall 2006)
  • Marcus Krause-Akelbein (Fall 2006)
  • Manuel Röthlingshöfer (Fall 2006)


    Pictures from our February 2006 retreat online

    A collection of pictures taken at our recent retreat is now online.


    University of Karlsruhe among the finalists of the excellence initiative

    The University of Karlsruhe (TH) was chosen as one of the ten institutions in Germany to join the last round of selections of the excellence initiative . Karlsruhe was nominated in all three areas of excellence. C.R. is scheduled to present one of the new proposals in June.


    Additions to the Richert Research Group

  • Tanja Lommel (Spring 2006)
  • Katharina Heimann (Spring 2006)
  • Christopher Deck (Spring 2006)

  • Criegee Lecture 2006

    Prof. J. Fraser Stoddart (UCLA, California NanoSystems Institute) will deliver the 2006 Criegee Lecture on Thursday, July 6, 2006, 5:15 PM in the Criegee Lecture Hall. Guests are welcome!


    Nucleinsäurechemietreffen 2006

    The 2006 Nucleinsäurechemietreffen will be held at the University of Göttingen on September 22, 2006.


    Additions to the Richert Research Group

  • Kerstin Gießler
  • Dr. Shahid Soomro

  • U. Karlsruhe ranked among top 5 research universities

    The University of Karlsruhe (TH) was ranked second among German research universities in the 2005 CHE ranking. A recent ranking by the Spiegel magazine ranks U. Karlsruhe (TH) as number 5 among German universities and one of the few highly research active schools.


    Research opportunities for high school students

    Starting February 2005, four high school students from the greater Karlsruhe area are engaged in research projects offered by the Richert Group. The four were selected from a large pool of applicants by a committee in the Institute of Organic Chemistry. A secon group of students is pursuing research in the Podlech Group.


    Albert Eschenmoser to deliver 2005 Criegee Lecture

    Prof. Dr.Dr.h.c.mult. Albert Eschenmoser (ETHZ, Scripps) will deliver the 2005 Criegee Lecture at the University of Karlsruhe (TH) on May 12, 2005, 5 PM (c.t.), Criegee Lecture Hall.


    Pictures from our March 2005 retreat online

    A compilation of pictures taken at our recent retreat can now be viewed online.


    Thesis Wins Departmental Award

    Jan Roja's Ph.D. thesis, defended on December 16, was awarded the 2004 Fa. Wolff und Sohn Prize. The title of the thesis is: "Effekt von Substituenten auf die Bindungseigenschaften von Oligodeoxynucleotiden: Synthese, templatgesteuerte Reaktionen und Microarrays" (Effect of substituents on the binding properties of oligodeoxynucleotides: synthesis, template-directed reactions, and microarrays).


    Additions to the Richert Research Group

  • Stefan Kwintus (October 2004)
  • Michael Bächle (October 2004)

  • Poster Wins Award at National Meeting

    A poster entitled "Neue Ansätze zur Modifizierung von Oligonucleotiden auf der festen Phase" (New Approaches for Modifying Oligonucleotides on Solid Support) by Carolin Ahlborn, Peter Grünefeld, Thomas Kottysch and Clemens Richert won one of the few poster awards at the national meeting of the Organic Division of the German Chemical Society (ORCHEM, Bad Nauheim, fall 2004).